SOCLab

Assοciate Professor of Organic Chemistry

Contact: Office: +302610997909 Lab.: +302610996249 Fax: +302610962956 e-mail:  This e-mail address is being protected from spambots. You need JavaScript enabled to view it

Research Interests

Synthetic Organic and Medicinal Chemistry [main]

• Discovery and development of small organic molecules and of natural product analogues/ derivatives (e.g. abietanes; polyamines; endoperoxides; retinoids; psoralens) with anticancer (Hedgehod pathway inhibitors; Cancer Stem Cell differentiators; Anti-angiogenic agents), antibacterial (against MRSA strains) and antimalarial activity.
• Synthesis of Multitarget Inhibitors and of Hybrids or Bioconjugates aiming at improvement of the pharmacological profile of a bioactive compound

Mass Spectrometry [secondary]

• Synthesis of labeling reagents (heavy/ light) for applications in analysis by Mass Spectrometry.
• Solid Phase Synthesis of “chemical probes” for applications in Mass Spectrometry Proteomics.

Education

2003: Ph.D. in Chemistry, Department of Chemistry, University of Patras, Greece

1991: Diploma in Chemistry, Department of Chemistry, University of Patras, Greece

Professional training and academic appointments

2016-today : Associate Professor of Organic Chemistry, Department of Chemistry, University of Patras,

-2018 (April 11th to July 25th) : Visiting Professor for Research at  "La Sapienza" - Università di Roma, Italy

-2017 (September 11th to October 10th) : Visiting Professor at Universitè Paul Sabatier, Toulouse, France

2010-2016: Assistant Professor of Organic Chemistry, Department of Chemistry, University of Patras,

-2009 : Post Doctoral Fellow  (The research Council of Norway) at University of Bergen, Bergen, Norway

2006- 2010: Lecturer in Organic Chemistry, Department of Chemistry, University of Patras,

2005- 2006 : Post Doctoral Fellow (Greek Scholarship Foundation), Laboratory of Organic Chemistry, Department of Chemistry, University of Patras, Greece,

2005: Part-time Lecturer, Department of Pharmacy, University of Patras,

2003- 2005: Post Doctoral Researcher, Department of Chemistry, University of Patras, Greece,

1995- 1996 : Research Fellow (EU fellowship, HCM), Department of Chemistry, University of Calabria, Cosenza, Italy,

1994: Research Fellow (EU fellowship, HCM), Department of Chemistry, University of Minho, Braga, Portugal.

Scholarships

2009: Scholarship from The Research Council of Norway for postdoctoral research in the University of Bergen, Norway.

2005-2006:  Scholarship from Greek State Scholarships’ Foundation for postdoctoral research in Greece.

1994, 1995- 1996: Human Capital and Mobility Fellowship for research in the Universities of Braga and Calabria, respectively.

International Schools

October 2007: MAOS 2007 Microwave Assisted Organic Synthesis, San Francisco, CA, USA.

September 2004: Ischia Advanced School of Organic Chemistry (IASOC 2004), Ischia, ITALY.

June 1993 & July 1996: NATO Advanced Study Institute (ASI) on Mass Spectrometry in the Biomolecular Science, (NATO scholarship) in Lacco Ameno, Ischia and Altavilla Milicia, Palermo, ITALY respectively.

Invited Lectures

November 2017: Universidad Catòlica de Cordoba, Cordoba, Argentina, [a] Title: "Targeting drug resistance in cancer stem cells. Hedgehog pathway inhibitors- Taepeenin D" [b] Title: "Abietane diterpenes – high value natural precursors for the development of new antimicrobial agents".

September 2015: Universitè Paul Sabatier, Toulouse, France, Title: "Polyamine Bioconjugates".

February 2013: IPATIMUP- University of Porto, Porto, Portugal (COST ACTION CM1106), Title: “Total Synthesis of Acidic Retinoids: A Library of Potential Cancer Stem Cell Regulators”.

January 2012: University of Insubria, Varese, Italy, Title: “Mass Spectrometry techniques and applications on the analysis of biomolecules”.

November 2008: Kjemisk Institutt, University of Bergen, Bergen, Norway, Title: “Synthetic Studies Towards the Development of acidic retinoids and acid retinoid-psoralen conjugates and hybrids”.

October 2008: Workshop in the framework of international school of Doctorate “Bernadino Telesio School of Hard Sciences” University of Calabria, Cozenza, Italy, Title: “Synthetic Studies towards the Development of Acidic Retinoids and Acidic Retinoid-Psoralen Conjugates and Hybrids, Suitable for Structure-Activity Relationship Studies”.

September 2007: XXXI Convegno Nazionale della Diviosione di Chimica Organica della Societa Chimica Italiana (ATTI) University of Calabria, Cozenza, Italy, Title: “Synthetic Studies towards the Development of a Glutathione-based anticancer or antiviral drug delivery system”.

June 2007: ECTNA, Newly Appointed Academic Teaching Staff Residential Summer School, Sliema, Malta, Title: “Survival for new Lecturers”.

Teaching Activities

Undergraduate Courses: Synthetic Organic Chemistry (FGI), Special Topics of Organic Chemistry (Mass Spectrometry), Organic Chemistry of Functional Groups II, Experimental Organic Chemistry (I and II lab courses), Organic Chemistry Lab-course (Dept. of Biology).

Postgraduate Courses: Organic Synthesis of Drugs, Advanced Synthetic Organic Chemistry (FGI), Techniques for Purification and Identification/ Characterization of Synthetic Products (Mass Spectrometry Proteomics).

Publications

International Scientific Journals with Peer Review System:42

International Scientific Books: 1

Full CV

Citation Number and h-index